Epi 3 Ways

Emergency Department Pharmacist Catherine Platt joins the show today to discuss Epinephrine including some ways we use it as EMTs, AEMTs and Paramedics. We also will break down three different clinical trials that have shaped how we administer the drug leading to best practices in and out of the hospital. The studies used in this show are listed below for your reference. 

Simons, F. Estelle R., and Xiaochen Gu. “Epinephrine Absorption in Adults: Intramuscular versus Subcutaneous Injection.” www.jacionline.org/Article, J ALLERGY CLIN IMMUNOL, 5 Aug. 2001, www.jacionline.org/article/S0091-6749(98)701903/fulltext. 

Perkins, Gavin D., et al. “A Randomized Trial of Epinephrine in out-of-Hospital Cardiac Arrest: Nejm.” New England Journal of Medicine, 23 Aug. 2018, www.nejm.org/doi/full/10.1056/NEJMoa1806842#article_references. 

Cole, J. B., Knack, S. K., Karl, E. R., Horton, G. B., Satpathy, R., & Driver, B. E. (2019). Human Errors and Adverse Hemodynamic Events Related to “Push Dose Pressors” in the Emergency Department. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 15(4), 276–286. https://doi.org/10.1007/s13181-019-00716-z